The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.

Nat Genet · 2019 · PMC6551226 · PMID 31133748

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highly significantno p-value reported

Despite a low total number of cells with prolonged bi-allelic Tsix expression, the correlation between bi-allelic Tsix expression and reduced/dispersed Xist RNA clouds is highly significant ( Fig. 5F ).

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