In terms of outcome, more advanced disease showed less frequent resolution of disease, subretinal fluid, and exudation [ Table 4 ].[ 56 ] Trends in management over decades A recent review of 351 cases of Coats disease over a period of 45 years showed a positive trend in the management and outcome.[ 26 ] A comparative evaluation by decade (1970 vs. 1980 vs. 1990 vs. 2000 vs. 2010s) revealed no significant difference in the demographic features, presenting verbal visual acuity, Coats disease stage, location and clock hours of telangiectasia and aneurysms and neov
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