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Draft Genome Sequences of Two Streptococcus pneumoniae Strains Causing Invasive Infections in Children in Qatar.

Microbiol Resour Announc · 2019 · PMC6554613 · PMID 31171608

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a decreasing trendno p-value reported
Interestingly, although resistance to penicillin and macrolides among pediatric invasive pneumococcal isolates remains high in Qatar, a decreasing trend for the past few years has been reported, which might be related to the widespread use of PCV-7 and PCV-13 ( 9 ).

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