IL-Iβ+3954 C/T Polymorphism and Its Clinical Associations in Egyptian Sickle Cell Disease Patients.

Contrastingly, a highly significant difference in the frequency of occurrence of TT genotype versus the combined genotypes CC and CT in cases and controls was found [(p value= 0.006), OR (95% CI): 5.505 (1.460-20.756) ] i.e. the homozygous mutant genotype TT was more prevalent in cases compared to control group ( Table 2 ).

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