At this time, according to several studies published to date, SNPs located in the lncRNA locus showed a highly significant association with the susceptibility of a variety of human tumors. 19 , 20 , 21 , 22 For example, Yan H et al 22 suggested that rs55829688 polymorphism could increase GAS5 expression by interacting with TP63, which might aggravate the meylosuppression and in turn lead to poor prognosis in acute myeloid leukemia.
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Genetic variants in a long noncoding RNA related to Sunitinib Resistance predict risk and survival of patients with renal cell carcinoma.
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