Patterns of Ethambutol Ocular Toxicity in Extended Use Therapy.

Cureus · 2019 · PMC6559692 · PMID 31245197

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an increasing trendno p-value reported

Additionally, there is an increasing trend for physicians to use higher doses of ethambutol (up to 1200 mg/day), especially in drug-resistant tuberculosis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.