IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states.

This may be highly significant in the clinical development of new immunotherapy strategies targeting these often tissue- and tumour-resident cells and may point to previously-unappreciated cascades with potential to activate and re-educate immune stroma.

also in 132,142 other papers

This points to IgE-mediated cascades with potential to activate immune stroma and may be significant in the clinical development of strategies targeting tumour-resident macrophages.

also in 13,097 other papers