"Dual Disease" TgAD/GSS mice exhibit enhanced Alzheimer's disease pathology and reveal PrP<sup>C</sup>-dependent secretion of Aβ.

Sci Rep · 2019 · PMC6562043 · PMID 31189938

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a slight trendno p-value reported

Total Aβ was similar among the different cell treatments, although we noted a slight trend for a reduction in total Aβ in N2a-APPswe-PrP − cells and an increase in N2a-APPswe-PrP A116V cells, compared with N2a-APPswe-CTL cells (Fig. 6C ).

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