ZAP-70 Regulates Autoimmune Arthritis via Alterations in T Cell Activation and Apoptosis.

In case of the IL-17 we also saw a decreasing trend in the ZAP-70 +/− spleen cell culture supernatants when compared to the BALB/c, however this difference was not statistically significant (641.57 ± 83.96 vs. 798.16 ± 101.82) ( Figure 2 B).

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The serum levels of IL-17 and IL-4 were similar in the two groups, however IL-6 production showed an increasing trend in the serum of arthritic ZAP-70 +/− mice ( Figure 2 D). 3.3.

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