Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes: A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank.

Arthritis Rheumatol · 2019 · PMC6563114 · PMID 30615301

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borderline significantno p-value reported

However, considering a Bonferroni corrected P value of 0.0028, the LDL cholesterol–OA association findings ( P = 0.004 from multivariable MR) can be considered borderline significant, and replication in the UK Biobank further strengthened this observation.

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