Moreover, an overall trend amongst the 11βHSDs in both short‐ and long‐term phases was observed, wherein 11βHSD1 was higher in vehicle‐treated tissue than in TPA‐treated tissue, and conversely 11βHSD2 was higher in TPA‐treated tissues and lower in vehicle‐treated tissues (Figure 5 ).
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Harnessing the gatekeepers of glucocorticoids for chemoprevention of non-melanoma skin cancer.
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