Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells.

The following observations were made through analysis of cellular components, molecular function, and biological processes (see Supplementary Tables 2 – 4 ): We identified several highly significant terms associated with HLA class II molecules and, for some terms, CD74, including antigen processing and presentation of peptide or polysaccharide antigen via MHC class II and antigen processing and presentation of exogenous peptide antigen via MHC class II (both with p < 0.00001).

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