APRIL Induces a Novel Subset of IgA<sup>+</sup> Regulatory B Cells That Suppress Inflammation via Expression of IL-10 and PD-L1.

Front Immunol · 2019 · PMC6587076 · PMID 31258536

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highly significantno p-value reported

A highly significant correlation between APRIL and IL-10 levels is observed in the synovial fluid of inflammatory arthritis patients ( Figure 8I ), suggesting that APRIL modulates IL-10 production not only in mice but also in humans.

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