Application of Physiologically Based Pharmacokinetic Modeling to Predict Pharmacokinetics in Healthy Japanese Subjects.

For compound B, >97% of prediction errors were distributed between 1.25 and 2.0 across the dose range, and fell into category 1 (prediction error, 0.8–1.25) or 2 (prediction error, 0.5–2.0), with a slight trend of overprediction.

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