a decreasing trendP =0.03
an increasing trendP =0.03
Joinpoint analyses identified 2007 as the single inflection point among male patients with metastatic MB: there was an increasing trend in the incidence rates from 2004 to 2007 (APC, 48.5; 95% CI, 23.8 to 78.3; P =0.03), and a decreasing trend in the incidence rates from 2007 to 2013 (APC, -13.5; 95% CI, -18.0 to -8.7; P =0.03).