Barely Significant
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Cancer chromosome breakpoints cluster in gene-rich genomic regions.

Genes Chromosomes Cancer · 2019 · PMC6590459 · PMID 30479017

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The sentences

highly significantP < 0.0001actually significant
This association also remains highly significant in separate analyses of recurrent and nonrecurrent chromosome abnormalities as well as of specific subtypes of cancer ( P < 0.0001 for all comparisons).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.