Treatment-resistant depression as risk factor for substance use disorders-a nation-wide register-based cohort study.

Addiction · 2019 · PMC6593719 · PMID 30938020

Europe PMC DOI

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borderline significantno p-value reported

The adjusted risk was elevated with 23% among TRD patients for the outcome of any SUD ≤ 1 year after treatment start (HR 1.2; 95% CI = 1.1–1.4), with a borderline significant elevated risk after > 1 year (HR = 1.15; 95% CI = 1.0–1.3).

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