Clinical characteristic and fecal microbiota responses to probiotic or antidepressant in patients with diarrhea-predominant irritable bowel syndrome with depression comorbidity: a pilot study.

Meanwhile, the SDS score showed a decreasing trend (51.9 ± 4.9 vs . 60.5 ± 4.0, Z = −1.96, P = 0.05) [Figure 1 D].

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In terms of variations in the relative abundances of bacteria, the relative abundance of Dialister increased and that of Clostridium XVIII and Bifidobacterium decreased significantly after treatment with Bifico, while that of Acetivibrio , Collinsella , and Odofibacter showed an increasing trend.

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