This is possibly significant given that recent studies have shown that the behaviour (ability to divide and differentiate) of SC is profoundly influenced by the interaction of collagen molecules and stem cell receptors. 71 Compression of morbidity by soluble activin receptor type IIB treatment In this study, we show that antagonism of myostatin/activin signalling in Ercc1 Δ/− mice attenuated the development of ageing‐related changes not only of muscle but rather also of health overall.
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Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling.
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