Quantifying this redistribution as the ratio of membrane proximal to total Rab11 fluorescence, the value for Wt a-syn at high expression levels is 40% compared to 27% for Wt a-syn at low expression levels or 25% for EGFP at high expression levels, both highly significant differences (Fig. 5b ).
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Regulation of exocytosis and mitochondrial relocalization by Alpha-synuclein in a mammalian cell model.
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