In vitro genotoxicity of nitroimidazoles as a tool in the search of new trypanocidal agents.

Mem Inst Oswaldo Cruz · 2019 · PMC6598759 · PMID 31271593

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

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boldest claim

The sentences

extremely significantp < 0.001actually significant

The positive control, 160 μM MMS, induced an extremely significant (p < 0.001) genotoxic effect compared to the control group with a TAU mean value of 554.2 ± 9.9.

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highly significantno p-value reported

FINDINGS Compound 3 showed a significant DNA strand break effect through the in vitro CA and highly significant clastogenic and/or aneugenic effect in the CBMN.

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