Statin use and high-dose statin use after ischemic stroke in the UK: a retrospective cohort study.

A series of sensitivity analyses to cope with missing data did not change the main results, except that 1) the marginally significant associations (including myopathy associated with statin use; dementia, TIA and BMI≥35 associated with high-intensity statin use) in the main analysis vanished but IMD groups 2 and 3 were associated with slightly decreased use of statins when the analysis was restricted to those with individual IMD; and that 2) the associations of BMI≥35 with increased use of any statin and high-intensity statin vanished when the missing value of BMI was replaced by the 95th percentile value.

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First, the general trend ran parallel to an increasing trend in statin use prior to stroke, which accounted for less than 10% of patients in 2000 and over 40% in 2014, and these prior users of statins continued to use them after stroke in almost 90% of cases throughout 2000–2014.

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