highly significantp -value < 0.001
Based on frequencies in the Control gnomAD, the OR for the rs1687005 risk T-allele was 4.57 (95% CI 2.33–8.97) and the odds ratios for the rs12722600 risk T-allele was 9.88 (95% CI 5.71–17.09), both highly significant ( p -value < 0.001).