Barely Significant
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Functional systemic CD4 immunity is required for clinical responses to PD-L1/PD-1 blockade therapy.

EMBO Mol Med · 2019 · PMC6609910 · PMID 31273938

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highly significantno p-value reported
Differences between G1 and G2 cohorts were also highly significant (Fig 1 A).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.