Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival.

The ratio of CC3-positive to AP2-positive spots revealed a highly significant increase in the percentage of CC3-positive spots in the first arch of Clpex mutants (n = 2 or more sections from 3 WT and 6 Clpex mutants; Figure 6Q ; p=0.0045) We also observed apoptosis in the cranial neuroepithelium bilaterally at the dorsolateral hinge points in mutant sections ( Figure 6O,P ).

also in 132,142 other papers