As noted above, however, the first generations of replication-defective HSV-1 vectors were hindered by highly significant limitations, including toxicity and short-term expression of the transgenes ( Marconi et al., 1999 ).
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As noted above, however, the first generations of replication-defective HSV-1 vectors were hindered by highly significant limitations, including toxicity and short-term expression of the transgenes ( Marconi et al., 1999 ).