Significantly higher CXCL8 expression was found in metastatic ccRCC ( n = 20; p = 0.0001; Figure 5 F) compared to normal tissue, and a positive trend was observed in relation to tumor grade and advanced stage in ccRCC patients (Figure 5 G).
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IL-8 and CXCR1 expression is associated with cancer stem cell-like properties of clear cell renal cancer.
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