Canine IL4-10 fusion protein provides disease modifying activity in a canine model of OA; an exploratory study.

PLoS One · 2019 · PMC6622543 · PMID 31295306

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

borderline significancep = 0.057so close (0.05 < p ≤ 0.1)

Cartilage damage Evaluation of Saf O stained cartilage sections showed a small increase in OARSI cartilage structural damage score in experimental (OA) knees compared to contralateral control knees (2.5 (95%CI: 0.6–4.4) points out of 12 points) in the PBS treated group, which was normalized in the cIL4-10 FP treated group (0.7 (95%CI: -0.6–2.0) points), at borderline significance (p = 0.057, Fig 8B ).

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