Reduced ribosomal RNA expression and unchanged ribosomal DNA promoter methylation in oral squamous cell carcinoma.

Mol Genet Genomic Med · 2019 · PMC6625366 · PMID 31169368

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a decreasing trendno p-value reported

The results showed that RNA expression for 28S ( p = 0.030), 18S ( p = 0.042), and 5.8S ( p = 0.028) mature rRNA was significantly lower in OSCC tissues than those in normal control tissues, and a decreasing trend without statistical difference for 45S precursor rRNA was presented in OSCC tissues (Figure 2 ).

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