Nobiletin and Derivatives: Functional Compounds from Citrus Fruit Peel for Colon Cancer Chemoprevention.

At half the original concentration present in the colon, there is a decreasing trend of cells in S phase and G2/M phase but an increasing trend was noted in the G0/G1 phase.

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Researchers are attempting to explore multiple avenues for novel leads as anti-cancer agents with an increasing trend to focus on natural sources like plants and fruits [ 6 , 7 , 8 ].

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