Response Predictors in Chronic Migraine: Medication Overuse and Depressive Symptoms Negatively Impact Onabotulinumtoxin-A Treatment.

Front Neurol · 2019 · PMC6635602 · PMID 31354606

Europe PMC DOI

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at the limit of significanceno p-value reported

( 32 ), in line with our results, also found depression and anxiety disorders to be associated to a lower responsiveness trend at the limit of significance.

also in 326 other papers

highly significantno p-value reported

These studies demonstrated that OnabotulinumtoxinA treatment not only significantly reduced the frequency of headache days but also showed highly significant improvements in multiple headache symptom measures and in patients' self-perceived quality of life.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.