Diverse immunotherapies can effectively treat syngeneic brainstem tumors in the absence of overt toxicity.

J Immunother Cancer · 2019 · PMC6637625 · PMID 31315671

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a trend towards significanceno p-value reported

Whole brain flow cytometry of mice treated with pmel T cells and VSV-hgp100 showed a significant increase in pmel (Thy1.1+) T cells three days after the last VSV dose, and a trend towards significance for endogenous (Thy1.1-) CD4 and CD8 T cells compared to monotherapy or untreated mice (Fig. 5 A).

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