A Real-Time Early Warning System for Monitoring Inpatient Mortality Risk: Prospective Study Using Electronic Medical Record Data.

Among these features, the proposed EWS recognized several historical clinical utilization features as highly significant predictors of in-hospital deterioration, including ED visits, inpatient admissions, and outpatient visits and clinical costs in the prior 12 months.

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Furthermore, when focusing on these top impactful chronic-based risk factors, we found that only the diagnoses of cardiovascular diseases, congestive heart failure, or renal diseases were still significantly associated with the mortality outcome, whereas other chronic-based features failed to attain significance in terms of odds ratios (ORs) after applying the propensity score matching analysis in our study ( Multimedia Appendix 8 ).

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