Biosynthetic homeostasis and resilience of the complement system in health and infectious disease.

EBioMedicine · 2019 · PMC6642076 · PMID 31262714

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a small trendno p-value reported

However, there was a small trend in pathway specificity: lower infant levels were found for peptides from proteins at the beginning of the classical pathway (C1QA, C1QB, C1R).

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an increasing trendno p-value reported

Most of the peptides show an increasing trend during aging ( Fig. 4 c–e) and a limited number of these peptides had significantly lower levels in individuals of ≤6 months: C1QA (SLG), C1QB (FDH), C1QC (FQS) C1R (GYG), C5 (ILS, ITH, ELS), C8 (MES, IPG), C9 (VVE, LSP, TSN), C4BP (LSL, ALL), ficolin-3 (LLG), CFAB (DAQ, STG, YGL), and clusterin (ASS, IDS).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.