Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5.

Front Immunol · 2019 · PMC6652118 · PMID 31379819

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may be significantno p-value reported

Lactate and hexokinase have also recently been found to inhibit RIG-I and MDA5 by interacting with MAVS, which may be significant in explaining the interplay between metabolism and immune signaling as glycolysis was found to be greatly decreased upon RLR signaling ( 329 ).

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