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Global burden of latent multidrug-resistant tuberculosis: trends and estimates based on mathematical modelling.

Lancet Infect Dis · 2019 · PMC6656782 · PMID 31281059

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a worrying trendno p-value reported
Our estimates signal a worrying trend of an increasing burden of latent MDR tuberculosis in children younger than 15 years.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.