A p- value less than 0.05 was considered significant; highly significant <.01; very highly significant <.001. 3 Result 3.1 Determination of nephrotoxicity dose model To establish the nephrotoxicity dose model, the animals were divided into three different groups: healthy control (CON), group-1 (treated with 100 mg gentamycin/kg/day; i.p.), and group-2 (treated with 150 mg gentamycin/kg/day; i.p).
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Renoprotective effects of stevia (<i>Stevia rebaudiana</i> Bertoni), amlodipine, valsartan, and losartan in gentamycin-induced nephrotoxicity in the rat model: Biochemical, hematological and histological approaches.
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