Dependency Between Protein-Protein Interactions and Protein Variability and Evolutionary Rates in Vertebrates: Observed Relationships and Stochastic Modeling.

(To provide the sense of scale, EMD is roughly equal to the area between the two distributions’ empirical CDFs, or cumulative distribution functions—therefore, a difference between, for example, EMD of 360.83 and 116.1, as shown in Table 2 , is highly significant; similarly, ED is a linear function of the Cramer Distance, with the same scale sensitivity).

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