Dissociable age and memory relationships with hippocampal subfield volumes in vivo:Data from the Irish Longitudinal Study on Ageing (TILDA).

Sci Rep · 2019 · PMC6662668 · PMID 31358771

Europe PMC DOI

hedged sentences

0.0650

closest p · 1.3× alpha

0.0860

boldest claim

The sentences

marginally significantp < 0.065so close (0.05 < p ≤ 0.1)

Subfield x cubic DR interactions were significant for CA1 ( p < 0.007), GC-DG ( p < 0.023), and molecular layer ( p < 0.016), with a marginally significant cubic term for CA4 ( p < 0.065); the cubic term did not reach significance for CA2/3 ( p > 0.1), but the quadratic term was significant ( p < 0.029) (Fig. 1b , top; Tables 2 & 3 , right).

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a marginal trendp < 0.08so close (0.05 < p ≤ 0.1)

In the same model, subfield x quadratic age interactions were significant for subiculum ( p < 0.0001), CA1 ( p < 0.005), molecular layer ( p < 0.0001), and hippocampal tail ( p < 0.0001), with a marginal trend for GC-DG (lin. p < 0.08, quad. p < 0.005; see Fig. 1a , bottom; Tables 2 & 3 , left).

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a weak trendp < 0.086so close (0.05 < p ≤ 0.1)

Further, subfield x quadratic age interactions were significant for subiculum ( p < 0.0001), molecular layer ( p < 0.001), hippocampal tail ( p < 0.0001), with a weak trend for CA1 (lin. p < 0.086, quad. p < 0.02; Fig. 1b , bottom; Tables 2 & 3 , right).

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