Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer's disease.

Sci Rep · 2019 · PMC6662857 · PMID 31358793

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highly significantno p-value reported

Consistent with our results showing a highly significant effect of fingolimod on astrocytes and microglia, numerous studies in primary cells and animal models neurological diseases indicate that microglia and astrocytes are central to the therapeutic effects of fingolimod 10 , 31 – 37 .

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