Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome.

Acta Pharm Sin B · 2019 · PMC6664040 · PMID 31384534

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a decreasing trendno p-value reported

However, the reason why TNF- α has a decreasing trend after 6 h of treatment with CDN and MCC950 may be related to the subsequent immune inflammatory response mediated by inhibition of IL-1 β production 51. , 52. , but the underlying mechanism needs further study.

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