Extracorporeal carbon dioxide removal for acute hypercapnic exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial.

Trials · 2019 · PMC6664508 · PMID 31362776

Europe PMC DOI

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highly significantno p-value reported

The clinical relevance of this work is potentially highly significant—both the mechanisms and outcomes of ECCO2R in AECOPD are the subject of research efforts and clinical interest.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.