highly significantp < 0.001
Data were statistically analysed following ANOVA one way or two way test, followed by the post-hoc Tukey test, with differences considered significant ( p < 0.05, * or lowercase letter), very significant ( p < 0.01, ** or bold lowercase letter), highly significant ( p < 0.001, *** or capital letter) or very highly significant ( p < 0.0001, **** or bold capital letter).