Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility.

Nat Commun · 2019 · PMC6671959 · PMID 31371763

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hedged sentences

0.0010

closest p · 0.0× alpha

0.0600

boldest claim

The sentences

highly significantp < 0.001actually significant

The quantitative data confirmed the previous qualitative observation in revealing a highly significant increased incidence of Type 1 cells in Cyfip1 +/− (LME: χ 2 (1) = 68.49, p < 0.001, Fig. 4c ).

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marginally significantp = 0.06so close (0.05 < p ≤ 0.1)

In this part of the task, 45 , 46 , the Cyfip1 +/− rats continued to respond to the original S + over successive sessions, while the WT began to switch their choices to the new S + (a 2 × 2 ANOVA revealed a main effect of SESSION ( F (3,39) = 3.67, p < 0.05) and a GENOTYPE × SESSION interaction ( F (3,39) = 3.76, p < 0.05), where a main effect of GENOTYPE was marginally significant ( F (1,13) = 4.32, p = 0.06)).

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