Barely Significant
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Association network analysis identifies enzymatic components of gut microbiota that significantly differ between colorectal cancer patients and healthy controls.

PeerJ · 2019 · PMC6673421 · PMID 31392094

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a decreasing trendno p-value reported
As we can see, in the order from healthy, to adenoma and CRC samples, there is a decreasing trend of node degree among the enzymes enriched in healthy controls (nodes with blue circles).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.