We observed a decreasing trend in drug efficacy as a function of increasing historic drug pressure, yet further research is needed to identify factors that are contributing to this variation and to determine whether reduced efficacy can be linked with the known β-tubulin SNPs.
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Therapeutic efficacy of albendazole against soil-transmitted helminthiasis in children measured by five diagnostic methods.
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The sentences
When focusing on the drug efficacy estimated by single Kato-Katz, there was an obvious trend between the drug pressure and drug efficacy for each of the three STH species.