The enrichment analysis revealed a highly significant positive correlation with the regulation of signal transduction (GO-term) and EGFR TKI resistance, different solid cancer types, namely pancreatic, prostate, and NSCLC as well as ErbB and HIF-1 signaling (KEGG pathway, Supplemental Tables S6 and S7 ). 4.
← all excerpts
Induction of Acquired Resistance towards EGFR Inhibitor Gefitinib in a Patient-Derived Xenograft Model of Non-Small Cell Lung Cancer and Subsequent Molecular Characterization.
1
—
—