Elucidation of the Molecular Mechanism Underlying <i>Lippia citriodora</i>(Lim.)-Induced Relaxation and Anti-Depression.

Interestingly, 100 mg/Kg body weight VEE-treated mice showed a highly significant increase of immobility time compared to negative and positive controls starting from day 4 of the test with 202.64 s, which gradually decreased to attain 177.63 s on the 7th day ( Figure 2 ).The low immobility time of the depressant mice receiving only water compared the VEE-treated mice suggested that the effect observed was not a result of the stress induced by TST, but because of the induction of relaxation by VEE, which is a unique effect of VEE. 2.3.

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