Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer.

Cells · 2019 · PMC6678810 · PMID 31336942

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fell short of significanceno p-value reported

Although the results obtained in blood fell short of significance by a narrow margin ( P -value VCAN 0.052, SDC3 0.055, Supplementary Figure S3 ) the impact of the tumour microenvironment has to be taken into account since both genes are also expressed in other cell types, such as macrophages, endothelial cells, and fibroblasts [ 48 , 49 , 50 ].

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a considerable trend toward significanceno p-value reported

However, VCAN and SDC3 transcripts were elevated in the blood of ovarian cancer patients and showed a considerable trend toward significance ( Supplementary Figure S3 , P -values: VCAN = 0.052, SDC3 = 0.055).

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