84 , 85 , 86 , 87 , 88 , 89 While the large size of goldfish embryos was previously advantageous, this advantage became almost insignificant after manipulation techniques were established in zebrafish. 70 , 84 Moreover, goldfish provides no obvious benefits to researchers who are purely interested in molecular developmental genetics, as goldfish require large aquarium systems and long periods of time for maintenance and spawning. 83 Ind
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